How it works
The 2019 version replaced the vague "minimal", "thin" and "thick" of the original with measurements, and defines a nodule by size and the angle it makes with the wall. The class is set by the most worrying feature present:
| Class | Defining features (CT and MRI) | Malignancy | Management |
|---|---|---|---|
| I | Thin (≤ 2 mm) smooth wall; homogeneous simple fluid (−9 to 20 HU, or CSF-like signal); no septa or calcification. Wall may enhance. | ≈ 0 % | None |
| II | Thin smooth wall with a few (1–3) thin septa (may enhance) or calcification of any type; or a homogeneous mass that is ≥ 70 HU unenhanced, 21–30 HU portal venous, > 20 HU and non-enhancing, or too small to characterise; at MRI, homogeneous and markedly T1- or T2-hyperintense. | < 1 % | None |
| IIF | Smooth minimally thickened (3 mm) enhancing wall or septa; or many (≥ 4) smooth thin enhancing septa; at MRI also a mass heterogeneously hyperintense on unenhanced fat-suppressed T1. | low (≈ 5–10 %) | Imaging at 6 and 12 months, then yearly to 5 years |
| III | One or more enhancing thick (≥ 4 mm) or irregular (≤ 3 mm obtuse-margined convex protrusions) walls or septa. | ≈ 50 % | Urology: surgery, ablation or surveillance |
| IV | One or more enhancing nodules: ≥ 4 mm convex protrusion with obtuse margins, or any size with acute margins. | ≈ 90 % | Urology: treatment |
- Enhancement is ≥ 20 HU at CT or ≥ 15 % signal increase at MRI. Thickened or nodular components that do not enhance, heterogeneous non-enhancing masses, and masses seen only without contrast cannot be classified; MRI with subtraction is the usual next step.
- Do not apply the system to infectious, inflammatory or vascular lesions, or to masses that are more than about a quarter solid.
- Malignancy figures are the approximate rates quoted in the classification paper and later series; class IIF rates vary widely between studies.
References
- Silverman SG, Pedrosa I, Ellis JH, et al. Bosniak Classification of Cystic Renal Masses, Version 2019: An Update Proposal and Needs Assessment. Radiology. 2019;292(2):475–488. doi:10.1148/radiol.2019182646 · free full text
- Schieda N, Davenport MS, Krishna S, et al. Bosniak Classification of Cystic Renal Masses, Version 2019: A Pictorial Guide to Clinical Use. RadioGraphics. 2021;41(3):814–828. doi:10.1148/rg.2021200160